Publications

Selected Publications

Kang W; Bang-Berthelsen CH; Holm A; Houben AJ; Müller AH; Thymann T; Pociot F; Estivill X; Friedländer MR, 2017. Survey of 800+ data sets from human tissue and body fluid reveals xenomiRs are likely artifacts.  RNA 23(4):433-445

Friedländer MR; Lizano E; Houben AJ; Bezdan D; Báñez-Coronel M; Kudla G; Mateu-Huertas E; Kagerbauer B; González J; Chen KC; LeProust EM; Martí E; Estivill X, 2014. Evidence for the biogenesis of more than 1,000 novel human microRNAs.  Genome Biol 15(4):R57

Lappalainen T; Sammeth M; Friedländer MR; ‘t Hoen PA; Monlong J; Rivas MA; Gonzàlez-Porta M; Kurbatova N; Griebel T; Ferreira PG; Barann M; Wieland T; Greger L; van Iterson M; Almlöf J; Ribeca P; Pulyakhina I; Esser D; Giger T; Tikhonov A; Sultan M; Bertier G; MacArthur DG; Lek M; Lizano E; Buermans HP; Padioleau I; Schwarzmayr T; Karlberg O; Ongen H; Kilpinen H; Beltran S; Gut M; Kahlem K; Amstislavskiy V; Stegle O; Pirinen M; Montgomery SB; Donnelly P; McCarthy MI; Flicek P; Strom TM; Lehrach H; Schreiber S; Sudbrak R; Carracedo A; Antonarakis SE; Häsler R; Syvänen AC; van Ommen GJ; Brazma A; Meitinger T; Rosenstiel P; Guigó R; Gut IG; Estivill X; Dermitzakis ET, 2013. Transcriptome and genome sequencing uncovers functional variation in humans.  Nature 501(7468):506-11

Friedländer MR; Mackowiak SD; Li N; Chen W; Rajewsky N, 2012. miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades.  Nucleic Acids Res 40(1):37-52

Friedländer MR; Chen W; Adamidi C; Maaskola J; Einspanier R; Knespel S; Rajewsky N, 2008. Discovering microRNAs from deep sequencing data using miRDeep.  Nat Biotechnol 26(4):407-15

Publications

Zapata L; Susak H; Drechsel O; Friedländer MR; Estivill X; Ossowski S, 2017. Signatures of positive selection reveal a universal role of chromatin modifiers as cancer driver genes.  Sci Rep 7(1):13124

Yan X; Wang Z; Westberg-Rasmussen S; Tarbier M; Rathjen T; Tattikota SG; Peck BCE; Kanke M; Oxvig C; Frystyk J; Starup-Linde J; Sethupathy P; Friedländer MR; Gregersen S; Poy MN, 2017. Differential Impact of Glucose Administered Intravenously and Orally on Circulating miR-375 Levels in Human Subjects.  J Clin Endocrinol Metab 102(10):3749-3755

Bustamante M; Hernandez-Ferrer C; Sarria Y; Harrison GI; Nonell L; Kang W; Friedländer MR; Estivill X; González JR; Nieuwenhuijsen M; Young AR, 2017. The acute effects of ultraviolet radiation on the blood transcriptome are independent of plasma 25OHD3.  Environ Res 159:239-248

Nejedla M; Li Z; Masser AE; Biancospino M; Spiess M; Mackowiak SD; Friedländer MR; Karlsson R, 2017. A Fluorophore Fusion Construct of Human Profilin I with Non-Compromised Poly(L-Proline) Binding Capacity Suitable for Imaging.  J Mol Biol 429(7):964-976

Kang W; Bang-Berthelsen CH; Holm A; Houben AJ; Müller AH; Thymann T; Pociot F; Estivill X; Friedländer MR, 2017. Survey of 800+ data sets from human tissue and body fluid reveals xenomiRs are likely artifacts.  RNA 23(4):433-445

Ferreira PG; Oti M; Barann M; Wieland T; Ezquina S; Friedländer MR; Rivas MA; Esteve-Codina A; Rosenstiel P; Strom TM; Lappalainen T; Guigó R; Sammeth M, 2016. Sequence variation between 462 human individuals fine-tunes functional sites of RNA processing.  Sci Rep 6:32406

Gowda NK; Kaimal JM; Masser AE; Kang W; Friedländer MR; Andréasson C, 2016. Cytosolic splice isoform of Hsp70 nucleotide exchange factor Fes1 is required for the degradation of misfolded proteins in yeast.  Mol Biol Cell 27(8):1210-9

Pantano L; Friedländer MR; Escaramís G; Lizano E; Pallarès-Albanell J; Ferrer I; Estivill X; Martí E, 2016. Specific small-RNA signatures in the amygdala at premotor and motor stages of Parkinson's disease revealed by deep sequencing analysis.  Bioinformatics 32(5):673-81

Tattikota SG; Rathjen T; Hausser J; Khedkar A; Kabra UD; Pandey V; Sury M; Wessels HH; Mollet IG; Eliasson L; Selbach M; Zinzen RP; Zavolan M; Kadener S; Tschöp MH; Jastroch M; Friedländer MR; Poy MN, 2015. miR-184 Regulates Pancreatic β-Cell Function According to Glucose Metabolism.  J Biol Chem 290(33):20284-94

Rivas MA; Pirinen M; Conrad DF; Lek M; Tsang EK; Karczewski KJ; Maller JB; Kukurba KR; DeLuca DS; Fromer M; Ferreira PG; Smith KS; Zhang R; Zhao F; Banks E; Poplin R; Ruderfer DM; Purcell SM; Tukiainen T; Minikel EV; Stenson PD; Cooper DN; Huang KH; Sullivan TJ; Nedzel J; Bustamante CD; Li JB; Daly MJ; Guigo R; Donnelly P; Ardlie K; Sammeth M; Dermitzakis ET; McCarthy MI; Montgomery SB; Lappalainen T; MacArthur DG, 2015. Human genomics. Effect of predicted protein-truncating genetic variants on the human transcriptome.  Science 348(6235):666-9

Kang W; Friedländer MR, 2015. Computational Prediction of miRNA Genes from Small RNA Sequencing Data.  Front Bioeng Biotechnol 3:7

Friedländer MR; Lizano E; Houben AJ; Bezdan D; Báñez-Coronel M; Kudla G; Mateu-Huertas E; Kagerbauer B; González J; Chen KC; LeProust EM; Martí E; Estivill X, 2014. Evidence for the biogenesis of more than 1,000 novel human microRNAs.  Genome Biol 15(4):R57

Cowled C; Stewart CR; Likic VA; Friedländer MR; Tachedjian M; Jenkins KA; Tizard ML; Cottee P; Marsh GA; Zhou P; Baker ML; Bean AG; Wang LF, 2014. Characterisation of novel microRNAs in the Black flying fox (Pteropus alecto) by deep sequencing.  BMC Genomics 15:682

Greger L; Su J; Rung J; Ferreira PG; Lappalainen T; Dermitzakis ET; Brazma A, 2014. Tandem RNA chimeras contribute to transcriptome diversity in human population and are associated with intronic genetic variants.  PLoS One 9(8):e104567

't Hoen PA; Friedländer MR; Almlöf J; Sammeth M; Pulyakhina I; Anvar SY; Laros JF; Buermans HP; Karlberg O; Brännvall M; den Dunnen JT; van Ommen GJ; Gut IG; Guigó R; Estivill X; Syvänen AC; Dermitzakis ET; Lappalainen T, 2013. Reproducibility of high-throughput mRNA and small RNA sequencing across laboratories.  Nat Biotechnol 31(11):1015-22

Lappalainen T; Sammeth M; Friedländer MR; 't Hoen PA; Monlong J; Rivas MA; Gonzàlez-Porta M; Kurbatova N; Griebel T; Ferreira PG; Barann M; Wieland T; Greger L; van Iterson M; Almlöf J; Ribeca P; Pulyakhina I; Esser D; Giger T; Tikhonov A; Sultan M; Bertier G; MacArthur DG; Lek M; Lizano E; Buermans HP; Padioleau I; Schwarzmayr T; Karlberg O; Ongen H; Kilpinen H; Beltran S; Gut M; Kahlem K; Amstislavskiy V; Stegle O; Pirinen M; Montgomery SB; Donnelly P; McCarthy MI; Flicek P; Strom TM; Lehrach H; Schreiber S; Sudbrak R; Carracedo A; Antonarakis SE; Häsler R; Syvänen AC; van Ommen GJ; Brazma A; Meitinger T; Rosenstiel P; Guigó R; Gut IG; Estivill X; Dermitzakis ET, 2013. Transcriptome and genome sequencing uncovers functional variation in humans.  Nature 501(7468):506-11

Miñones-Moyano E; Friedländer MR; Pallares J; Kagerbauer B; Porta S; Escaramís G; Ferrer I; Estivill X; Martí E, 2013. Upregulation of a small vault RNA (svtRNA2-1a) is an early event in Parkinson disease and induces neuronal dysfunction.  RNA Biol 10(7):1093-106

Li N; You X; Chen T; Mackowiak SD; Friedländer MR; Weigt M; Du H; Gogol-Döring A; Chang Z; Dieterich C; Hu Y; Chen W, 2013. Global profiling of miRNAs and the hairpin precursors: insights into miRNA processing and novel miRNA discovery.  Nucleic Acids Res 41(6):3619-34

Song JL; Stoeckius M; Maaskola J; Friedländer M; Stepicheva N; Juliano C; Lebedeva S; Thompson W; Rajewsky N; Wessel GM, 2012. Select microRNAs are essential for early development in the sea urchin.  Dev Biol 362(1):104-13

Friedländer MR; Mackowiak SD; Li N; Chen W; Rajewsky N, 2012. miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades.  Nucleic Acids Res 40(1):37-52

Sharbati S; Friedländer MR; Sharbati J; Hoeke L; Chen W; Keller A; Stähler PF; Rajewsky N; Einspanier R, 2010. Deciphering the porcine intestinal microRNA transcriptome.  BMC Genomics 11:275

Stoeckius M; Maaskola J; Colombo T; Rahn HP; Friedländer MR; Li N; Chen W; Piano F; Rajewsky N, 2009. Large-scale sorting of C. elegans embryos reveals the dynamics of small RNA expression.  Nat Methods 6(10):745-51

Friedländer MR; Adamidi C; Han T; Lebedeva S; Isenbarger TA; Hirst M; Marra M; Nusbaum C; Lee WL; Jenkin JC; Sánchez Alvarado A; Kim JK; Rajewsky N, 2009. High-resolution profiling and discovery of planarian small RNAs.  Proc Natl Acad Sci U S A 106(28):11546-51

Ender C; Krek A; Friedländer MR; Beitzinger M; Weinmann L; Chen W; Pfeffer S; Rajewsky N; Meister G, 2008. A human snoRNA with microRNA-like functions.  Mol Cell 32(4):519-28

Friedländer MR; Chen W; Adamidi C; Maaskola J; Einspanier R; Knespel S; Rajewsky N, 2008. Discovering microRNAs from deep sequencing data using miRDeep.  Nat Biotechnol 26(4):407-15

Publication list retrieved from NCBI using ImpactPubs

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