Friedländer lab receives research grant from Cancerfonden
We are grateful for the generous grant from Cancerfonden – which will fund our efforts to discover cancer-specific microRNAs that are not present in healthy tissues. Such microRNAs could arise from perturbed cellular states and would be ideal biomarkers and drug targets. The grant will cover a new PhD position (see our JOIN US section)!
MapToCleave method to profile microRNA biogenesis in living cells published in Cell Reports
This study used a screening approach to measure microRNA biogenesis of >10,000 RNA structures in living cells and complemented with studying microRNA expression in hundreds of tissues from 20 animal species from MirGeneDB. It was conducted in collaboration with the Fromm lab and the GOLD lab. Read the full study here.
Internship in Co-profiling of protein and RNA expression in single cells
We are seeking a highly motivated and enthusiastic master’s student to join the team for a 4-months research internship (ECTS or paid) starting September 2021.
The focus of this research project is to study novel microRNA-mediated functions in single cells by implementing an innovative single-cell protein and RNA co-profiling technique. Under close supervision by a postdoctoral researcher, the student will apply several molecular biology techniques such as proximity extension assay (PEA), microfluidic cell sorting, antibody conjugation, PCR, electrophoresis and RNA sequencing. Experience in molecular and cellular biology are required, with possibility in gaining insight into bioinformatics sequencing analysis. Finally, successful contribution to the project would be acknowledged as co-authorship on a research publication.
If you are interested in joining an international team of ambitious and friendly scientists, please send your CV and motivation letter describing your background and research interest to Marc Friedländer (marc.friedlander@scilifelab.se).
Update: this position is no longer available.
Friedländer Lab BBQ
The Friedländer lab is welcoming summer in Stockholm and celebrating that our senior scientist Bastian has landed a very attractive (tenure-track and start-up) group leader position in Tromsø, Norway.
SPARC: New co-profiling approach predicts cellular states more accurately
New study on Pleistocene tissue samples pioneering research on ancient RNA
Research highlight from our latest study on the oldest sequenced RNA from a 14300 year old wolf was published on SciLiifeLab news site. Read the complete article here.
Marcel successfully defended his PhD thesis today
We congratulate Marcel on a successful dissertation defence today! Great work, Doctor Marcel Tarbier!!!
Marcel nailed his thesis
Marcel nailed his PhD thesis at SciLifeLab and MBW, Stockholm University.
Wenjing successfully defended her PhD thesis today
We congratulate Wenjing on a successful dissertation defence today! Great work, Doctor Wenjing Kang!!! Wenjing Kang is the first PhD from Friedländer Lab.
Studying gene synchronicity in mammalian single cells
Research highlight from our latest study on gene co-expression in single-cells was published on SciLiifeLab news site. Read the complete article here.
Small regulator genes may have the answers to big questions
Marc Friedländer’s research highlights published at Stockholm University news. Read the news article here.
Nuclear gene proximity and protein interactions shape transcript covariances in mammalian single cells
Wenjing nailed her thesis today
Wenjing nailed her PhD thesis at SciLifeLab and MBW, Stockholm University today. She is now gearing up for the defence which is in a few weeks.
Kavan is moving on to do PhD at EMBL
Kavan, master thesis student in our lab, is embarking on an exciting journey to do his PhD at EMBL. He is starting his PhD studies later this month in the group of Olivier Duss, EMBL.